Arthritis Curehow to Arthritis Cure for
Initial laboratory research at UEA has found that a compound in broccoli called sulforaphane blocks the enzymes that cause joint destruction in osteoarthritis – the most common form of arthritis.
Broccoli has previously been associated with reduced cancer risk but this is the first major study into its effects on joint health.
With funding from both Arthritis Research UK and the Diet and Health Research Industry Club (DRINC), the £650,000 (R6,005,060.75) project will explore how sulforaphane may act to slow or prevent the development of osteoarthritis.
First patient trial
It will prepare the way for the first patient trials and could lead to safe new ways of preventing and treating this painful disease.
Sulforaphane is a bioactive compound found in cruciferous vegetables, particularly broccoli. Eating broccoli leads to a high level of sulforaphane in the blood, but scientists don''s School of Biological Sciences, who is leading the research said: ""
As part of the three-year project, the UEA team will also investigate the effects of other dietary compounds on osteoarthritis, including diallyl disulphide which is found in high amounts in garlic and also appears to slow the destruction of cartilage in laboratory models. (EurekAlert/ September 2010)
Outward-facing knees: osteoarthritis riskOutward-facing knees: osteoarthritis risk